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QJM Advance Access published online on June 27, 2005

QJM, doi:10.1093/qjmed/hci091
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© The Author 2005. Published by Oxford University Press on behalf of the Association of Physicians. All rights reserved. For Permissions, please email: journals.permissions@oupjournals.org
Received December 3, 2004
Revised May 10, 2005

Original paper

Control of hypertension in patients at high risk of cardiovascular disease

B. Roca 1*, C. Suárez 2, Á. Ceballos 3, J.M. Varela 4, F. Nonell 5, J. Montes 6, J. Sobrino 5, A. de la Peña 7, and for the CIFARC Group

1 From the Hospital General, Castellón, University of Valencia, Spain
2 From the Hospital de la Princesa, Madrid, Spain
3 From the Hospital de Antequera, Antequera (Málaga), Spain
4 From the Hospital Virgen del Rocío, Sevilla, Spain
5 From the Hospital l'Esperit Sant, Santa Coloma de Gramanet (Barcelona), Spain
6 From the Hospital do Meixoeiro, Vigo (Pontevedra), Spain
7 From the Hospital Son Llàtzer, Palma de Mallorca, Spain

* To whom correspondence should be addressed.
B. Roca, E-mail: brocav{at}meditex.es


   Abstract

Background: Hypertension is a major cardiovascular risk factor, but knowledge about the real magnitude of the problem and its determinants is lacking.

Aim: To assess control of hypertension and evaluate medical resource use, in patients at high risk of cardiovascular disease.

Design: Multicentric cross-sectional study.

Methods: We collected data for 2205 adult patients from 36 centres, representative of all regions of Spain. Patients had attended out-patient clinics from July 2002 to August 2003, had an absolute cardiovascular risk >=20% at 10 years (according to the Framingham guidelines), and had a diagnosis of hypertension. Pregnant and terminally ill patients were excluded.

Results: Hypertension was inadequately controlled in 1384 patients (62.8%). LDL cholesterol was higher in patients with uncontrolled hypertension (median 130.2 vs. 120.0 mg/dl, p < 0.001). Haemoglobin A1c in diabetic patients was also greater in those with uncontrolled hypertension (median 7.10% vs. 6.90%, p = 0.010). Uncontrolled hypertension was associated with the following variables, in descending strength of association: higher LDL cholesterol, taking antihypertensive medication, living in non-metropolitan areas, and higher body mass index.

Discussion: Hypertension is poorly controlled in most patients with a high risk of cardiovascular disease. Uncontrolled hypertension is frequently associated with poor control of other risk factors.


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