QJM vol. 98 no. 2 © Association of Physicians 2005; all rights reserved.
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Heart rate variability measurements and the prediction of ventricular arrhythmias
From the Department of Emergency Medicine, Royal Infirmary of Edinburgh, Edinburgh, and 1Cardiodigital Ltd, Elvingston Science Centre, Gladsmuir, UK
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| Introduction |
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Heart rate variability (HRV) is the temporal variation between sequences of consecutive heartbeats. On a standard electrocardiogram (ECG), the maximum upwards deflection of a normal QRS complex is at the peak of the R wave (Figure 1), and the duration between two adjacent R wave peaks is termed the R-R interval. The ECG signal requires editing before HRV analysis can be performed, a process requiring the removal of all non-sinus-node-originating beats. The resulting period between adjacent QRS complexes resulting from sinus node depolarizations is termed the N-N (normal-normal) interval.1 HRV is the measurement of the variability of the N-N intervals.
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Although counter-intuitive, it is possible that HRV confers a survival advantage. Any system exhibiting intrinsic variability is primed to respond rapidly and appropriately to demands placed upon it.
HRV is a measure of the balance between sympathetic mediators of heart rate
| The history of HRV |
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| Problems with measuring HRV |
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| Measuring HRV |
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| HRV and the onset of VTAs |
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| Conclusions and further work |
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Address correspondence to Dr M.J. Reed, Emergency Department, Royal Infirmary of Edinburgh, 51 Little France Crescent, Edinburgh EH16 4SA. e-mail: mattreed1@hotmail.com
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