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QJM 2005 98(2):87-95; doi:10.1093/qjmed/hci018
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QJM vol. 98 no. 2 © Association of Physicians 2005; all rights reserved.

Review

Heart rate variability measurements and the prediction of ventricular arrhythmias

M.J. Reed, C.E. Robertson and P.S. Addison1

From the Department of Emergency Medicine, Royal Infirmary of Edinburgh, Edinburgh, and 1Cardiodigital Ltd, Elvingston Science Centre, Gladsmuir, UK

The first 150 words of the full text of this article appear below.


    Introduction
 
Heart rate variability (HRV) is the temporal variation between sequences of consecutive heartbeats. On a standard electrocardiogram (ECG), the maximum upwards deflection of a normal QRS complex is at the peak of the R wave (Figure 1), and the duration between two adjacent R wave peaks is termed the R-R interval. The ECG signal requires editing before HRV analysis can be performed, a process requiring the removal of all non-sinus-node-originating beats. The resulting period between adjacent QRS complexes resulting from sinus node depolarizations is termed the N-N (normal-normal) interval.1 HRV is the measurement of the variability of the N-N intervals.


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Figure 1. The normal electrocardiogram with component waves labelled.

 
Although counter-intuitive, it is possible that HRV confers a survival advantage. Any system exhibiting intrinsic variability is primed to respond rapidly and appropriately to demands placed upon it.

HRV is a measure of the balance between sympathetic mediators of heart rate . . . [Full Text of this Article]


    The history of HRV
 

    Problems with measuring HRV
 

    Measuring HRV
 

    HRV and the onset of VTAs
 

    Conclusions and further work
 

Address correspondence to Dr M.J. Reed, Emergency Department, Royal Infirmary of Edinburgh, 51 Little France Crescent, Edinburgh EH16 4SA. e-mail: mattreed1@hotmail.com


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