Q J Med 2003; 96: 211-215
© 2003 Association of Physicians
Clinical experience and pre-test probability scores in the diagnosis of pulmonary embolism
From the Canterbury Respiratory Research Group and 1 Department of Medicine, Christchurch School of Medicine and Health Sciences, University of Otago, New Zealand
Received 16 October 2002 Accepted for publication 9 December 2002.
Background: The Geneva and Wells pre-test probability scores are intended to replace empirical assessment of patients with suspected pulmonary embolism (PE). The effect of clinical experience on the inter-rater variability of these scores, and on empirical judgement, is unknown.
Aim: To determine whether medical staff appointment grade affects the inter-rater variability of these pre-test probability scores, or empirical assessment, in patients with suspected PE.
Design: Questionnaire survey.
Methods: Doctors were grouped by grade (mean number of years since graduation±SEM): house officers 0.7±0.2, registrars 6.3±0.6, consultants 25±4 and applied pre-test probability scores to actual case scenarios.
Results: The Geneva score was the most consistent method of determining pre-test probability and was unaffected by clinical experience (Geneva 
=0.73, Wells =0.38, empirical =0.23, p<0.001 ). With empirical judgement, inter-rater variability was inversely proportional to clinical experience (house officers =0.37, registrars =0.24, consultants = 0.16, p<0.05).
Discussion: The Geneva score was the least variable method and can be applied by junior or senior doctors. Using empirical judgement, junior doctors were more likely to agree on the pre-test probability of PE than were their more senior colleagues. This may imply that as physicians gain experience, they recognize that the diagnosis of PE can be difficult to assess and are reluctant to exclude it on clinical grounds.
Address correspondence to Dr S. Iles, Canterbury Respiratory Research Group, Hagley Hostel, Christchurch Hospital, Private Bag 4710, New Zealand. e-mail: stephen.iles{at}chmeds.ac.nz
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