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Q J Med 2003; 96: 27-54
© 2003 Association of Physicians


Review

Diagnosis and management of vertebral artery stenosis

G.C. Cloud and H.S. Markus

From the Division of Clinical Neuroscience, St George's Hospital Medical School, London, UK

The first 150 words of the full text of this article appear below.


    Introduction
 
Approximately one-quarter of ischaemic strokes involve the posterior or vertebrobasilar circulation.1,2 Stenosis of the vertebral artery can occur in either its extra- or intracranial portions, and may account for up to 20% of posterior circulation ischaemic strokes.3–6 Stenotic lesions, particularly at the origin of the vertebral artery, are not uncommon. In an angiographic study of 4748 patients with ischaemic stroke, some degree of proximal extracranial vertebral artery stenosis was seen in 18% of cases on the right and 22.3% on the left.7 This was the second most common site of stenosis after internal carotid artery stenosis at the carotid bifurcation. Such stenotic lesions are now potentially treatable by endovascular techniques.8

In marked contrast with carotid artery stenosis, the optimal management of vertebral artery stenosis has received limited attention, and is poorly understood. This partly reflects difficulties in imaging the vertebral artery adequately, and limited surgical treatment options. Recent improvements in . . . [Full Text of this Article]


    Anatomy
 

    Extracranial vertebral artery stenosis
 

    Intracranial vertebral stenosis
 

    The role of imaging in diagnosis
 

    Treatment
 
Medical treatment
Surgical treatment
Endovascular treatment

    Conclusion
 

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