Q J Med 2002; 95: 137-142
© 2002 Association of Physicians
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Cerebral venous sinus thrombosis
From the Wessex Neurological Centre, Southampton General Hospital, Southampton, UK
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Introduction |
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Cerebral (dural) venous sinus thrombosis is an uncommon condition, but its clinical presentation is varied and often dramatic. It often affects young-to-middle-aged patients, and more commonly women. Although recognized for more than 100 years,1 it has only in recent years come to be diagnosed frequently ante-mortem. This is partly due to greater awareness among physicians and neurologists, and partly to improved non-invasive imaging techniques.
We have no reliable data on its incidence, nor on geographical or racial differences in susceptibility. According to British death certification data from 1952 to 1961, the average mortality from venous sinus thrombosis was 0.4/106/year over this period.3 Assuming a mortality rate of 10–20% over this period produces an incidence figure of 4–8/106/year, which is likely to be an underestimate.
Data from a US study in 1993–4 estimated that dural sinus thrombosis might complicate 11.6/100 000 deliveries, although mortality in this survey was zero.
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Anatomy |
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Aetiology |
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Clinical presentation |
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Complications |
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Diagnosis |
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Therapy |
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Outcome |
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Conclusions |
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Notes |
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References |
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