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Q J Med 2001; 94: 113-114
© 2001 Association of Physicians

Correspondence

Dose-dependent seizure activity associated with fluoxetine therapy

A. Oke, V. Adhiyaman, K. Aziz and A. Ross

Department of General Geriatric Medicine, Wrexham Maelor Hospital, Wrexham

Sir,

Fluoxetine (Prozac) is a selective serotonin reuptake inhibitor (SSRI). It is licensed for the treatment of depression, obsessive-compulsive disorder and bulimia nervosa. It is thought to have a low adverse effect profile compared to conventional tricyclic antidepressants (TCA). Here we report a patient who experienced seizures following escalation of fluoxetine dose.

A 53-year-old female was admitted following an episode of generalized tonic-clonic convulsions . . . [Full Text of this Article]

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