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Q J Med 2000; 93: 839-841
© 2000 Association of Physicians

Correspondence

A. Siebenhofer, A.J. Sutton and B. Williams

University of Graz Austria Department of Epidemiology and Public Health, University of Leicester, UK Cardiovascular Research Institute, Leicester, UK

Increased augmentation index and systolic stress in type 1 diabetes mellitus

Sir,

Wilkinson et al.1 have shown that type 1 diabetic patients have increased augmentation index, which is an indicator for increased systemic arterial stiffness. These findings were in contrast to our observations in a group of 46 consecutive type 1 diabetic patients and 51 controls, who were referred to the Royal Infirmary Leicester, UK.

Forty-six type 1 diabetic patients (30 males) with mean age 38 (SD 12.8) years, BMI 27 (5.3) kg/m2, mean heart rate 78 (14) bpm, mean blood pressure 95 (9.8) mmHg, mean diabetes duration 16 (10.2) years and HbA 9.8 (1.8)% were compared with 51 well-matched controls . . . [Full Text of this Article]

References

I.B. Wilkinson, J.R. Cockcroft and D.J. Webb

Clinical Pharmacology Unit, University of Cambridge Department of Cardiology, University of Wales College of Medicine, Cardiff Clinical Pharmacology Unit and Research Centre, University of Edinburgh