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QJM Advance Access originally published online on July 31, 2008
QJM 2008 101(11):899-900; doi:10.1093/qjmed/hcn098
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© The Author 2008. Published by Oxford University Press on behalf of the Association of Physicians. All rights reserved. For Permissions, please email: journals.permissions@oxfordjournals.org

Clearance of acanthosis nigricans associated with insulinoma following surgical resection

S. Ghosh, B. Roychowdhury, S. Mukhopadhyay and S. Chowdhury

From the Department of Endocrinology, Institute of Post Graduate Medical Education & Research, Calcutta, India

Address correspondence to S. Ghosh, Department of General Medicine, Ayr hospital, Dalmellington road, Ayr, South Ayrhire, KA6 6DK, UK. email: drsujoyghosh{at}rediffmail.com


  Abstract

Acanthosis nigricans is said to be a marker of insulin resistance. It is known to occur in patients with insulinoma where there is marked hyperinsulinaemia. We report a case wherein the acanthosis disappeared following surgical resection of insulinoma and this strengthens the hypothesis that hyperinsulinaemia is responsible for acanthosis.


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