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QJM Advance Access originally published online on April 21, 2007
QJM 2007 100(5):311-312; doi:10.1093/qjmed/hcm026
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© The Author 2007. Published by Oxford University Press on behalf of the Association of Physicians. All rights reserved. For Permissions, please email: journals.permissions@oxfordjournals.org

Cold agglutinin disease revealing mediastinal seminoma

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Sir,

Cold agglutinin disease (CAD) is an autoimmune haemolytic anaemia in which cold-reactive auto-antibodies bind to erythrocyte carbohydrate antigens, causing hemagglutination and complement-mediated haemolysis.1–4 It is associated with various conditions, including infections (Mycoplasma pneumoniae, hepatitis C), autoimmune diseases (especially systemic lupus erythematosus) and lymphoproliferative disorders (mainly lymphoma.1–8 However, it has rarely been described . . . [Full Text of this Article]

F. Hervé, M. Debled, C. Houdent, H. Levesque and I. Marie

Department of Internal Medicine
Rouen University Hospital
Rouen
France

email: isabelle.marie@chu-rouen.fr


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