QJM Advance Access originally published online on October 15, 2007
QJM 2007 100(11):685-689; doi:10.1093/qjmed/hcm085
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The under use of thromboprophylaxis in older medical in-patients: a regional audit
From the 1Department of Medicine for the Elderly, St James's University Hospital, Leeds, 2Department of Medicine for the Elderly, York Hospital, York, 3Hull and York Medical School/Department of Health Science, University of York, York, UK, and 4Department of Medical Gerontology. Trinity Centre of Health Sciences, St James's Hospital, Dublin, Eire
Address correspondence to Dr A. South, Department of Medicine for the Elderly, St James's University Hospital, Beckett Street, Leeds LS9 7TF, UK. email: alsouthuk{at}yahoo.co.uk
Received 23 March 2007 and in revised form 4 July 2007
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Abstract |
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Background: The risk of venous thromboembolism (VTE) among medical in-patients increases with age. Thromboprophylaxis using low-molecular-weight heparin can reduce the incidence by 50%, but anecdotally is under-used in medical patients, particularly the elderly.
Aim: To examine prescribing practice for thromboprophylaxis in elderly in-patients in the Yorkshire region.
Design: Regional audit of medical records and drug charts.
Methods: A simultaneous audit was done of all medical in-patients >75 years on 30 wards in 10 hospitals. Guidelines published by the Scottish Intercollegiate Guidelines Network (SIGN) on the use of thromboprophylaxis were used as the standard. Data were collected on contraindications and/or indications for thromboprophylaxis and the type of prophylaxis used.
Results: Of 601 patients studied (mean age 84.6 years), 117 (19.5%) had indications for thromboprophylaxis with no contraindications. Of these 117, 34 (29%) were receiving prophylaxis as per guidelines. There was more than one indication for thromboprophylaxis in 17% of those left untreated. The mean age of those receiving therapy was similar to those not receiving it (84.0 vs. 84.5 years, p = 0.66, t-test). Elderly in-patients on medical wards were more likely to receive appropriate treatment than those on geriatric wards (43% vs. 23%, p = 0.03, 
2 test).
Discussion: Thromboprophylaxis is under-used in older medical in-patients, despite their increased risk of VTE, particularly on geriatric wards. Greater consideration by doctors attending to older medical patients is needed if VTE is to be prevented.