QJM Advance Access published online on September 10, 2008
QJM, doi:10.1093/qjmed/hcn120
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Neurocysticercosis
Sir,I read with interest the article by Ntusi and Horsfall.1 The authors may not have considered neurocysticercosis, the most common parasitic disease of the central nervous system, as a possible diagnosis in the case described. Neurological manifestations of echinococcosis and neurocysticercosis are similar. While the patient's serology for echinococcosis was positive, a cross reaction with Taenia solium infection is a major problem.2–4 Also, prolonged therapy with albendazole is effective for neurocysticercosis.5 Attempts to search for Taenia must be made before the authors conclude that such cysts are caused from echinococcosis.
Hua Chiew Hospital, Bangkok 10100, Thailand
email: weekitti{at}gmail.com
References
1. Ntusi NA, Horsfall C. Severe disseminated hydatid disease successfully treated medically with prolonged administration of albendazole. Q J Med (2008) 101:745–6.[Web of Science]
2. Poretti D, Felleisen E, Grimm F, Pfister M, Teuscher F, Zuercher C, et al. Differential immunodiagnosis between cystic hydatid disease and other cross-reactive pathologies. Am J Trop Med Hyg (1999) 60:193–8.[Abstract]
3. Virginio VG, Hernández A, Rott MB, Monteiro KM, Zandonai AF, Nieto A, et al. A set of recombinant antigens from Echinococcus granulosus with potential for use in the immunodiagnosis of human cystic hydatid disease. Clin Exp Immunol (2003) 132:309–15.[CrossRef][Web of Science][Medline]
4. García HH, Gonzalez AE, Evans CA, Gilman RH. Cysticercosis Working Group in Peru. Taenia solium cysticercosis. Lancet (2003) 362:547–56.[CrossRef][Web of Science][Medline]
5. Garcia HH. Del Brutto OH; Cysticercosis Working Group in Peru. Neurocysticercosis: updated concepts about an old disease. Lancet Neurol (2005) 4:653–61.[CrossRef][Web of Science][Medline]
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