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QJM Advance Access originally published online on July 23, 2008
QJM 2008 101(10):828; doi:10.1093/qjmed/hcn091
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© The Author 2008. Published by Oxford University Press on behalf of the Association of Physicians. All rights reserved. For Permissions, please email: journals.permissions@oxfordjournals.org

Pseudohyponatremia in elderly patients

sir,

I read with interest the article by Gankam Kengne and colleagues.1 The elderly participants in the article have multiple chronic conditions but the authors do not mention any lipid disorders. Both hypertriglyceridemia and hypercholesterolemia can cause pseudohyponatremia2,3, a laboratory artifact occurring when serum is measured by means of common, indirect techniques. Lipid profile and serum osmolality must be performed before the authors conclude that measured hyponatremia is contributed to the risk of fracture.

W. Kittisupamongkol

Hua Chiew Hospital, Bangkok 10100, Thailand email: weekitti{at}gmail.com

References

1. Gankam Kengne F, Andres C, Sattar L, Melot C, Decaux G. Mild hyponatremia and risk of fracture in the ambulatory elderly. Q J Med (2008) 101:583–8.[Web of Science]

2. Turchin A, Seifter JL, Seely EW. Clinical problem-solving. Mind the gap. N Engl J Med (2003) 349:1465–9. Erratum in: N Engl J Med 2004; 350:629.[Free Full Text]

3. Weisberg LS. Pseudohyponatremia: a reappraisal. Am J Med (1989) 86:315–8.[CrossRef][Web of Science][Medline]


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This Article
Right arrow Extract Freely available
Right arrow FREE Full Text (PDF) Freely available
Right arrow All Versions of this Article:
101/10/828    most recent
hcn091v1
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