QJM Advance Access originally published online on April 25, 2008
QJM 2008 101(8):669-671; doi:10.1093/qjmed/hcn055
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© The Author 2008. Published by Oxford University Press on behalf of the Association of Physicians. All rights reserved. For Permissions, please email: journals.permissions@oxfordjournals.org
Churg–Strauss syndrome associated with montelukast therapy
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Sir,
A 47-year-old woman had a 4-year history of severe asthma. Because asthma continued to deteriorate, montelukast therapy was instituted in April 2007. On September 2007, the patient presented with painful cutaneous manifestations of 1-month duration that had progressively developed, involving her elbows and hands. On admission, the patient was febrile (38°C). Physical examination revealed diffuse sibilant rales, bilaterally. Cutaneous examination demonstrated skin nodules involving her elbows and the back of her hands (Figure 1
Department of Internal Medicine
CHU de Rouen
Rouen University Hospital
76031 Rouen Cedex
France
email: isabelle.marie@chu-rouen.fr