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QJM 2005 98(3):234-236; doi:10.1093/qjmed/hci032
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The Author 2005. Published by Oxford University Press on behalf of the Association of Physicians. All rights reserved. For Permissions, please email: journals.permissions@oupjournals.org

Correspondence

Evaluating acid-base disorders

R.P. Cole

Holy Name Hospital Teaneck USA e-mail: rc18@columbia.edu

The first 10% of the full text of this article appears below.

Sir,

In their review of acid-base disturbances in cholera, Zalunardo et al. illustrate the limitations of the conventional approach when dealing with complex clinical situations.1 The patient with cholera was thought to have both contraction metabolic alkalosis and metabolic acidosis from bicarbonate losses in diarrhoea, with the combination leading to a relatively normal arterial pH, PCO2, and plasma bicarbonate concentration. A different approach to these issues was introduced by Stewart2,3 and supported by Fencl4 and Kellum,5 among others. In this development, acid-base disorders can be considered to arise from alterations in three independent variables: . . . [Full Text of this Article]

M.L. Halperin

St Michael's Hospital University of Toronto Canada


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