Q J Med 2003; 96: 611-613
© 2003 Association of Physicians
Correspondence |
Hypokalaemic thyrotoxic periodic paralysis in the UK
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Sir,
I read with interest the article Severe hypokalaemia in a Chinese male by Lin et al.1 In Western countries, most cases of hypokalaemic periodic paralysis (HPP) are due to autosomal dominant familial periodic paralysis (FPP), but in an Asian population, thyrotoxic periodic paralysis (TPP) is the most common cause.15 The age of onset, race, family history, medications and underlying disease states can help in identifying the cause of HPP.6 Initial therapy of the patient with HPP includes potassium (K+) replacement and search for underlying aetiology. Further management depends on the aetiology of hypokalaemia.6 TPP is common in Asian and Hispanic individuals, and uncommon in Whites and Afro-Americans.15,8,9 As patients of Oriental ethnicity are
Department of Medicine
Tameside General Hospital
Ashton-under-Lyne
e-mail: ranjitsinharay@hotmail.com