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Q J Med 2003; 96: 459-460
© 2003 Association of Physicians

Biologic

The new mapping

Colin Berry

The first 10% of the full text of this article appears below.

The new techniques of experimental biology have greatly increased the powers of resolution of classical embryological science. Some are very sophisticated, some direct—it is perhaps surprising (or a mammalian conceit) that it took so long to realise that the Zebra fish was an experimental animal you could see through as things developed. What is gained from increasing sophistication is sometime surprising and sometimes counter-intuitive, but it is fair to say that it gradually moves us to a unified, if complex, view of how tissues and organs are developed. The neural crest is a good exemplar.

The neural crest is unique to vertebrates—it has been called the fourth germ layer, and ’ordinary’ anatomy has shown that the cells of the neural crest, like the other germ layers, form a transient population that exists only during development. By straightforward . . . [Full Text of this Article]


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