Q J Med 2003; 96: 315-316
© 2003 Association of Physicians
Correspondence |
Metformin-associated lactic acidosis in a patient with liver disease
Department of Diabetes and Endocrinology Department of Gerontology Department of Intensive Care, Central Middlesex Hospital, London Department of Diabetes and Metabolism, The Royal London Hospital, London e-mail: Tahseen.Chowdhury@bartsandthelondon.nhs.uk
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Sir,
Metformin is an orally active biguanide, and was found to reduce mortality and complications in obese diabetic patients in the UK Prospective Diabetes Study.1 As a result, the drug is widely used as first-line therapy for patients with obesity and type 2 diabetes. We would like to remind prescribers of a rare, but commonly fatal complication of