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Q J Med 2003; 96: 175-176
© 2003 Association of Physicians

Biologic

Failing dogma and a sloppy code

Colin Berry

The first 10% of the full text of this article appears below.

We have all been brought up—post Watson and Crick—on the mantra ‘one gene, one protein’ and have probably regarded antibodies as a special case, if we bothered about the exceptions to the rule. This starting point has led to singular interpretations of what we might do with a reading of the genetic code—some presentations to the public have led them to suppose that there will be a disease (and a cure) per faulty gene. All we need is a good reading system that will tell us where to look for a marker, and that in turn will tell us how to attack the disease process. But it really is not like that at all.

The advent of ‘A user's guide to the human genome’1 a clear guide around the system, does not help the casual molecular biologist/physician much in the attempt to . . . [Full Text of this Article]


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