Q J Med 2003; 96: 868-869
© 2003 Association of Physicians
Correspondence |
Acute pancreatitis and exacerbation of hepatitis B following reduced dose of prednisolone
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Sir,
Hepatitis virus type B (HBV) infects the pancreas1,2 and may cause acute pancreatitis.15 Immunosuppressive therapy results in enhanced replication of HBV and depressed host immunity. The discontinuation of therapy causes a rebound of the immune system, resulting in development of hepatitis. Here, we report a patient with underlying HBV infection, who had acute/non-fluminant hepatitis with acute pancreatitis after a decrease in dose of an immunosuppressive agent.
A 48-year-old Japanese male HBV
Second Department of Internal Medicine University of the Ryukyus Okinawa Japan. e-mail: ooshiro@aol.com