Q J Med 2002; 95: 487-488
© 2002 Association of Physicians
Biologic |
Flies in the colon
| The first 10% of the full text of this article appears below. |
Any regular reader of this column will have noticed a preoccupation with developmental pathology. This is a personal interest, but depends on a conviction that the mechanisms of development, properly understood, are central to the development of most degenerative disease and of much other pathology. The latest surprise is about carcinoma of the colon.
The Adenomatous Polyposis Coli (APC) tumour suppressor gene is known to be affected in