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Q J Med 2002; 95: 253-255
© 2002 Association of Physicians

Correspondence

Recurrent venous thromboses, anti-cardiolipin antibodies and Crohn's disease

B.Y.H. Thong and H.H. Chng

Department of Rheumatology, Allergy and Immunology, Tan Tock Seng Hospital, Singapore

C.L. Ang

Singapore National Eye Centre, Singapore

M.S. Ho

Raffles Hospital, Singapore

Sir,

Inflammatory bowel disease (IBD), which is relatively uncommon in Orientals, is associated with an increased frequency of thromboembolism. Thromboembolic disease is a significant cause of morbidity and mortality in patients with IBD. The mechanism of enhanced procoagulant activity is not well understood. We report a case of a middle-aged Chinese man who presented with bilateral central retinal vein occlusions (CRVO), deep venous thrombosis, anticardiolipin antibodies (ACA) and intermittent per rectal bleeding as the predominant manifestations of Crohn's disease (CD).

A 43-year-old Chinese businessman first presented in June 1994 with acute onset of visual blurring in the left eye. He was diagnosed with CRVO and was treated topically by the attending ophthalmologist. . . . [Full Text of this Article]

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