Q J Med 2002; 95: 128-130
© 2002 Association of Physicians
Correspondence |
Recovery from renal failure in malignant hypertension associated with primary aldosteronism: effect of an ACE inhibitor
Department of Internal Medicine III
Department of Pathology, Fukushima Medical University School of Medicine, Fukushima, Japan
Sir,
Primary aldosteronism is one of the most common causes of secondary hypertension. However, it is rare for this disease to induce malignant hypertension associated with vascular organ damage including renal failure.1 One of the reasons for this is that, even in the malignant phase, renin activity and subsequent angiotensin II production remain suppressed in primary aldosteronism. Here, we report a case with aldosterone-producing adenoma and increased renin activity complicated by malignant hypertension and renal failure, which required haemodialysis therapy. This case is noteworthy, because medical therapy with angiotensin-converting enzyme (ACE) inhibitor effectively improved renal function, allowing discontinuation of dialysis.
A 40-year-old woman
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