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Q J Med 2001; 94: 721-722
© 2001 Association of Physicians


Correspondence

Could factor V Leiden defect cause Addison's disease?

H. Soran, H.Y. Osman, N. Younis, S.A. Sukumar and D.A. Taberner

Department of Haematology South Manchester University Hospitals Manchester

Sir,

We describe a case of Addison's disease caused by bilateral suprarenal haemorrhage in a patient heterozygous for factor V Leiden defect. This is the first reported case of isolated bilateral suprarenal haemorrhage in a patient with this disorder. Because of the unique blood supply of the suprarenal glands, we believe that suprarenal haemorrhage was secondary to venous infarction caused by venous thrombosis in suprarenal veins and venous plexus.

A 68-year-old man was admitted to hospital with . . . [Full Text of this Article]

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