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Q J Med 2001; 94: 1-3
© 2001 Association of Physicians

Editorial

The rhinovirus—not such an innocent?

N.G. Papadopoulos and S.L. Johnston

Allergy and Clinical Immunology Unit, 2nd Department of Paediatrics, University of Athens, Greece National Heart and Lung Institute at St Mary's, Imperial College School of Medicine, London, UK

Human rhinoviruses (RVs) are probably the commonest pathogens afflicting mankind.1 They were isolated some four decades ago from common cold sufferers, and several epidemiological studies have confirmed that they are by far the commonest common cold viruses after the first years of life.2 However, in all these years, the general consensus was that the common cold, and consequently RVs, represented a mild nuisance, rather than a true disease, and not much attention has been paid to them. Evidence suggesting that RV infections can also produce serious complications came early,3 but since they involved immunocompromised patients, they were still considered exceptional. Nevertheless, data supporting the view that RV infection can result in considerable morbidity and even mortality has steadily increased, becoming compelling during recent years. Several factors have attributed to this change of view. Most certainly, our understanding of the epidemiology and complications of RV infections is now much clearer, partly . . . [Full Text of this Article]

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