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Q J Med 1999; 92: 547-550
© 1999 Association of Physicians

Editorial

Liver transplantation

J. Neuberger

Liver unit, Queen Elizabeth Hospital, Birmingham

Liver transplantation has come of age: the procedure is no longer considered experimental, indications and contra-indications are relatively clearly defined and agreed, and survival rates, at least in the short- and medium-term, are now acceptable, with most centres reporting five-year survival rates in excess of 70%. Coming of age is associated with maturity and (without wishing to overstretch a weak analogy) maturity is associated with new problems and challenges. In this editorial, some of the challenges and opportunities will be outlined.

The gap between the number of donors and the number of potential recipients is increasing. Thus, in the UK, between 1993 and 1997, the number of new registrations for liver transplantation rose from 569 to 698;1 the number of donors (this figure includes all offers of donation and includes those which are unsuitable for any reason, such as co-existing infection or malignancy) rose from 727 to 868; however, the . . . [Full Text of this Article]

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