QJM Advance Access originally published online on April 17, 2009
QJM 2009 102(6):431-433; doi:10.1093/qjmed/hcp043
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© The Author 2009. Published by Oxford University Press on behalf of the Association of Physicians. All rights reserved. For Permissions, please email: journals.permissions@oxfordjournals.org
Chronic kidney disease—assessing the impact
From the Nuffield Department of Medicine, University of Oxford, Oxford Kidney Unit, Churchill Hospital, Oxford OX3 7BN, UK
Address correspondence to Chris A. OCallaghan, Nuffield Department of Medicine, University of Oxford, Oxford Kidney Unit, Churchill Hospital, Oxford OX3 7BN, UK. email: chris.ocallaghan@ndm.ox.ac.uk
| The first 10% of the full text of this article appears below. |
Chronic kidney disease (CKD) is important. In a study of over a million people, CKD was associated with both increased mortality and age-standardized risk of cardiovascular disease, even when known risk factors were controlled for.1 Impaired kidney function has implications for prescribing and for the use of over the counter preparations, especially non-steroidal anti-inflammatory drugs. In addition, a proportion of people with moderately reduced kidney function will experience a progressive loss of kidney function. This will affect their health and may require renal replacement therapy with dialysis or kidney transplantation.
Unfortunately, we do not have a perfect method for the routine quantification of