QJM Advance Access originally published online on March 10, 2008
QJM 2008 101(5):419-421; doi:10.1093/qjmed/hcn028
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© The Author 2008. Published by Oxford University Press on behalf of the Association of Physicians. All rights reserved. For Permissions, please email: journals.permissions@oxfordjournals.org
Pulmonary actinomycosis in a patient with diffuse systemic sclerosis treated with infliximab
Department of Internal Medicine, Rouen University
Hospital, 76031 Rouen Cedex, France
Laboratory of Pneumology, Rouen University
Hospital, 76031 Rouen Cedex, France
email: isabelle.marie@chu-rouen.fr
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Opportunistic infections have been frequently reported in patients with acquired immunodeficiency syndrome (AIDS) or other conditions with compromised host defenses, such as malignancy and transplantation. More recently, opportunistic infections have also been increasingly reported in patients with connective tissue diseases, including systemic lupus erythematosus, systemic sclerosis and polymyositis/dermatomyositis.1, 2 Many factors, especially immunosuppressive medications, have been mentioned to account for the elevated frequency of opportunistic infections in these patients.1, 2 We report a case of Actinomyces meyeri pneumonia in a patient with diffuse cutaneous systemic sclerosis (dcSSc), which occurred shortly after institution of