QJM Advance Access originally published online on February 2, 2008
QJM 2008 101(3):245-247; doi:10.1093/qjmed/hcn005
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© The Author 2008. Published by Oxford University Press on behalf of the Association of Physicians. All rights reserved. For Permissions, please email: journals.permissions@oxfordjournals.org
Respiratory muscle weakness in a patient with quiescent Crohn's disease and pneumonia
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Sir,
A 33-year-old woman presented with a week's history of progressive backache, weakness and dysphagia. The onset of her symptoms coincided with tapering of 4-week course of oral corticosteroids (prednisolone), which was instituted to treat a severe pneumonic illness requiring admission to intensive care and a short period of assisted ventilation. She did not have any previous history of obstructive airways or interstitial pulmonary disease. Her respiratory illness was presumed to be due to viral pneumonia but no serological or microbiological evidence for infection was identified. She was diagnosed with Crohn's disease since as a child, based on histology of her colonoscopic biopsy. The bowel disease was quiescent for
Discussion
Department of Neurology and
Department of Neuropathology
Essex Centre for Clinical Neurosciences
Queen's Hospital
Rom Valley Way
Romford
Essex RM7 0AG
UK
email: chaudhuria@gmail.com