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QJM Advance Access originally published online on January 9, 2008
QJM 2008 101(2):163-164; doi:10.1093/qjmed/hcm141
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© The Author 2008. Published by Oxford University Press on behalf of the Association of Physicians. All rights reserved. For Permissions, please email: journals.permissions@oxfordjournals.org

Hyponatraemia due to renal proximal tubule dysfunction in a patient with adult-onset Still's disease

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Sir,

Adult-onset Still's disease (AOSD) is a systemic inflammatory disorder characterized by spiking fever, evanescent rash and multiple organ involvements. Renal involvement has been, however, rarely reported in AOSD. We report an unusual occurrence of proximal tubular dysfunctions presenting with hyponatraemia in a patient with AOSD.

A 56-year-old Japanese man was admitted after 1 week of high-grade intermittent fever, arthralgias and myalgias. Physical examination revealed polyarthritis and . . . [Full Text of this Article]

T. Sugimoto, M. Yasuda, M. Sakaguchi, N. Osawa, Y. Tanaka, T. Uzu and A. Kashiwagi

Department of Internal Medicine
Shiga University of Medical Science
Otsu, Shiga, 520-2192
Japan
email: toshiro@belle.shiga-med.ac.jp

H. Araki and M. Isono

Department of Medicine
Otsu Municipal Hospital
Otsu, Shiga 520-0804
Japan


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