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QJM 2008 101(1):67-68; doi:10.1093/qjmed/hcm107
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© The Author 2008. Published by Oxford University Press on behalf of the Association of Physicians. All rights reserved. For Permissions, please email: journals.permissions@oxfordjournals.org

Antibiotic hypersensitivity mimicking recurrent endocardits—identifying the culprit with the in vitro lymphocyte transformation test

The first 10% of the full text of this article appears below.

Sir,

The drug hypersensitivity syndrome is characterized by fever and systemic abnormalities including lymphopenia, lymphadenopathy, skin and visceral involvement mimicking systemic sepsis. The following case illustrates how the in vitro lymphocyte transformation test can be used to confirm drug hypersensitivity in this scenario, differentiating it from deteriorating infective endocarditis, hence avoiding progression to inappropriate interventions.

A 62-year-old man was admitted . . . [Full Text of this Article]

H.L. Cooper, C. Pickard, E. Healy and P.S. Friedmann

Dermatopharmacology Unit
University of Southampton
Southampton General Hospital
Tremona Road, Southampton
UK
email: hywel1@soton.ac.uk

P.W.X. Foley and J.M. Morgan

Wessex Cardiac Centre
Southampton University Hospitals Trust
Southampton General Hospital
Tremona Road, Southampton
UK


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