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Multislice computed tomography coronary angiography for triaging patients with positive radionuclide myocardial perfusion imaging
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Sir,
Myocardial perfusion imaging using single-photon emission computed tomography (SPECT) is the most commonly applied diagnostic imaging modality in patients with suspected coronary artery disease in the US, with more than 9 million procedures performed annually.1 The positive predictive value of SPECT is limited, and in a considerable number of patients with suspected perfusion deficits conventional coronary angiography shows no significant coronary stenoses. Multislice computed tomography (MSCT) coronary angiography allows the non-invasive assessment of coronary artery stenoses, and has a high negative predictive value.2–4 Thus, MSCT might be applied as a secondary gate-keeper in patients with positive SPECT, prior to deciding whether to perform conventional coronary
Department of Radiology
Department of Cardiology
Charité Medical School
Humboldt University and Free University
Berlin
Germany
email: marc.dewey@charite.de