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QJM 2007 100(9):597-598; doi:10.1093/qjmed/hcm070
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© The Author 2007. Published by Oxford University Press on behalf of the Association of Physicians. All rights reserved. For Permissions, please email: journals.permissions@oxfordjournals.org

Personal risk

John Launer

The first 10% of the full text of this article appears below.

How do you make the right decision about preventive treatment when n = 1 and you happen to be the ‘n ’ concerned? I recently had to do this for myself, and it has made me reflect on how I approach this with my patients, too.

My own dilemma related to taking warfarin. Many years ago I had a series of unexplained pulmonary micro-emboli. I was screened for all the known genetic factors, but no particular cause was found. However, my mother died suddenly in her early sixties from a massive pulmonary embolus, so a genetic influence seemed likely. My haematologist suggested that I should take long-term warfarin, . . . [Full Text of this Article]


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