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Personal risk
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How do you make the right decision about preventive treatment when n = 1 and you happen to be the n concerned? I recently had to do this for myself, and it has made me reflect on how I approach this with my patients, too.
My own dilemma related to taking warfarin. Many years ago I had a series of unexplained pulmonary micro-emboli. I was screened for all the known genetic factors, but no particular cause was found. However, my mother died suddenly in her early sixties from a massive pulmonary embolus, so a genetic influence seemed likely. My haematologist suggested that I should take long-term warfarin,