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Is there a role for low carbohydrate diets in the management of type 2 diabetes?
From the 1Manchester Diabetes Centre, and 2Manchester Royal Infirmary, Manchester, UK
Address correspondence to Miss J. Worth, Manchester Diabetes Centre, 193 Hathersage Road, Manchester M13 OJE, UK. email: joy.worth@cmmc.nhs.uk
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| Introduction |
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Type 2 diabetes mellitus (DM) is associated with excess mortality and morbidity. Individuals with type 2 DM are at a significantly higher risk for both microvascular and macrovascular complications. The condition is also increasing in epidemic proportions in both developed and developing nations, with the global diabetic population predicted to rise from 118 million in 1995 to 220 million in 2010.1–3
Obesity associated diabetes accounts for the overwhelming majority of cases of type 2 DM, and obesity is the single most important modifiable risk factor for type 2 DM. Recent studies have demonstrated the powerful effect of intensive lifestyle modification on preventing or delaying the onset of type 2 DM.4,5 Furthermore, weight loss of 10 kg in an obese individual is associated with a 30% reduction in diabetes-related mortality.6 These benefits are more difficult to replicate in the free-living population, however where conventional dietary strategies are associated with only modest
| What is the Atkins diet? |
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| Clinical trials on Atkins diet and its clinical efficacy |
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| Comparison of the Atkins Diet and nutritional recommendations for diabetes |
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| Modified CHO diets |
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| Conclusion |
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