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QJM Advance Access published online on October 3, 2008
QJM, doi:10.1093/qjmed/hcn118
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© The Author 2008. Published by Oxford University Press on behalf of the Association of Physicians. All rights reserved. For Permissions, please email: journals.permissions@oxfordjournals.org

Urban trench fever presenting as culture-negative endocarditis

N.E. Jenkins1, D.J.P. Ferguson2, N.J. Alp3, T.G. Harrison4 and I.C.J.W. Bowler1

From the 1Department of Infectious Diseases and Microbiology, 2Nuffield Department of Pathology, 3Department of Cardiovascular Medicine, University of Oxford, John Radcliffe Hospital, Oxford and 4Respiratory & Systemic Infection Laboratory, HPA Centre for Infections, London, UK

Address correspondence to N.E. Jenkins, Department of Infectious Diseases and Microbiology, John Radcliffe Hospital, Oxford, Oxon OX3 9DU, UK. email: njenkins{at}liv.ac.uk


  Abstract

A young Russian man presented with increasing shortness of breath and signs of worsening aortic regurgitation. A diagnosis of infective endocarditis was made before emergency valve replacement. The infective cause was not discovered by routine culture but was suggested by electron microscopy and confirmed by serology and PCR testing.


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