Skip Navigation

QJM 2004 97(9):555-567; doi:10.1093/qjmed/hch096
This Article
Right arrow Full Text Freely available
Right arrow FREE Full Text (PDF) Freely available
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in ISI Web of Science
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Add to My Personal Archive
Right arrow Download to citation manager
Right arrow Search for citing articles in:
ISI Web of Science (10)
Right arrowRequest Permissions
Right arrow Disclaimer
Google Scholar
Right arrow Articles by Panegyres, P.K.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Panegyres, P.K.
Social Bookmarking
Add to CiteULike   Add to Connotea   Add to Del.icio.us  
What's this?

QJM vol. 97 no. 9 © Association of Physicians 2004; all rights reserved.

Review

The contribution of the study of neurodegenerative disorders to the understanding of human memory

P.K. Panegyres

From the Mount Medical Centre, Perth, Australia

Memory impairment is one of the most common complaints affecting patients with neurodegenerative disorders, and its investigation has provided insights into the function and properties of human memory. The study of Alzheimer's disease has indicated the importance of mesial temporal structures and the hippocampus in episodic memory. In progressive supranuclear palsy, frontotemporal dementias, Parkinson's disease and Huntington's disease fronto-striatal networks are involved in working memory and higher level cognition. The study of semantic dementia, where there is lobar atrophy of the temporal lobe, has shown that the temporal neocortex has an important function in semantic memory. The investigation of human memory in neurodegenerative disorders suggests that the interaction of networks subserving episodic memory, semantic memory, and working memory contributes to higher level cognition and results in the fundamental homeostatic processes of recall and learning.

Address correspondence to Dr P.K. Panegyres, Neuregene Pty Ltd, The Mount Medical Centre, Suite 33, 146 Mounts Bay Road, Perth, Western Australia, 6000. e-mail: macfarlane4{at}optus.net.au


Add to CiteULike CiteULike   Add to Connotea Connotea   Add to Del.icio.us Del.icio.us    What's this?


This article has been cited by other articles:


Home page
 Arch NeurolHome page
J. Marshall, K. White, M. Weaver, L. Flury Wetherill, S. Hui, J. C. Stout, S. A. Johnson, X. Beristain, J. Gray, J. Wojcieszek, et al.
Specific Psychiatric Manifestations Among Preclinical Huntington Disease Mutation Carriers
Arch Neurol, January 1, 2007; 64(1): 116 - 121.
[Abstract] [Full Text] [PDF]

Home page
 Physiol. GenomicsHome page
N. Ruiz-Opazo and J. Tonkiss
Genome-wide scan for quantitative trait loci influencing spatial navigation and social recognition memory in Dahl rats
Physiol Genomics, September 14, 2006; 26(2): 145 - 151.
[Abstract] [Full Text] [PDF]

Home page
 GerontologistHome page
K. Dijkstra, M. Bourgeois, G. Youmans, and A. Hancock
Implications of an Advice-Giving and Teacher Role on Language Production in Adults With Dementia.
Gerontologist, June 1, 2006; 46(3): 357 - 366.
[Abstract] [Full Text] [PDF]


Disclaimer:
Please note that abstracts for content published before 1996 were created through digital scanning and may therefore not exactly replicate the text of the original print issues. All efforts have been made to ensure accuracy, but the Publisher will not be held responsible for any remaining inaccuracies. If you require any further clarification, please contact our Customer Services Department.