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Q J Med 1997; 90: 5-12
© 1997 Association of Physicians

Vertical transmission of human immunodeficiency virus

J. Morrison and N.J. Alp1

From the Nuffield Department of Obstetrics and Gynaecology, John Radcliffe Hospital Oxford, UK 1 Department of Medicine, John Radcliffe Hospital Oxford, UK

Address correspondence to Dr N.J. Alp, Wolfson College, Linton Road, Oxford OX2 6UD


  Abstract

We discuss the interactions between mother and infant that influence the transmission of HIV. Potential routes of infection are identified, and maternal and infant risk factors for transmission are explored. The role of the immune system in controlling HIV infection in the infant is discussed. Finally, preventive measures for reducing vertical transmission are proposed and evaluated.


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