Skip Navigation

This Article
Right arrow Full Text (PDF)
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Alert me to new issues of the journal
Right arrow Add to My Personal Archive
Right arrow Download to citation manager
Right arrowRequest Permissions
Right arrow Disclaimer
Google Scholar
Right arrow Articles by STAVROU, P.
Right arrow Articles by MURRAY, P. I.
Right arrow Search for Related Content
PubMed
Right arrow Articles by STAVROU, P.
Right arrow Articles by MURRAY, P. I.
Social Bookmarking
Add to CiteULike   Add to Connotea   Add to Del.icio.us  
What's this?

Q J Med 1993; 86: 719-725
© 1993 Association of Physicians

research-article

Ocular manifestations of classical and limited Wegener's granulomatosis

P. STAVROU, J. DEUTSCH, C. RENE, D. E. LAWS, R. A. LUQMANI1 and P. I. MURRAY

From the Birmingham and Midland Eye Hospital Birmingham, UK 1Department of Rheumatology, University of Birmingham Birmingham, UK

Address correspondence to Mr P. I. Murray, Academic Unit of Ophthalmology, Birmingham and Midland Eye Hospital, Church Street, Birmingham B3 2NS

Received 29 June 1993 Accepted for publication 17 July 1993.

Wegener's granulomatosis (WG) may be subdivided into two forms, classical and limited. The latter specifically excludes renal disease and carries a better prognosis. Both forms have sight-threatening complications, but the relative incidence of ocular manifestations in each is not well documented. Patients with limited (n = 15) and classical (n = 16) WG were ophthalmologically examined. Ocular abnormalities found included orbital and nasolacri-mal disease, corneo-scleral inflammation, dry eyes and retinal vein occlusion. In four patients (two from each group), no ocular disease was detected. The limited group included four potentially sight-threatening complications, compared to eight in the classical group. Overall, there was no statistically significant difference in any of the ocular manifestations between the two groups. Although treatment with corticosteroid and immunosuppressive agents has dramatically improved the prognosis of the disease, ocular morbidity is still well recognized. A combined medical and ophthalmological approach with prompt therapeutic intervention is recommended in these patients.


Add to CiteULike CiteULike   Add to Connotea Connotea   Add to Del.icio.us Del.icio.us    What's this?


This article has been cited by other articles:


Home page
 Br J OphthalmolHome page
M Wang, R N Khurana, and S R Sadda
Central retinal vein occlusion in Wegener's granulomatosis without retinal vasculitis.
Br J Ophthalmol, November 1, 2006; 90(11): 1435 - 1436.
[Full Text] [PDF]


Disclaimer: Please note that abstracts for content published before 1996 were created through digital scanning and may therefore not exactly replicate the text of the original print issues. All efforts have been made to ensure accuracy, but the Publisher will not be held responsible for any remaining inaccuracies. If you require any further clarification, please contact our Customer Services Department.