Q J Med 1991; 78: 185-190
© 1991 Association of Physicians
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Hypothalamic Syndrome and Central Sleep Apnoea Associated with Toluene Exposure

From the University Department of Medicine, Western General Hospital Crewe Road South, Edinburgh EH4 2XU
*Paediatric Department, Victoria Hospital Hayfield Road, Kirkcaldy, Edinburgh EH52 5SB
Department of Respiratory Medicine, City Hospital 51 Greenbank Drive, Edinburgh EH52 5SB
Accepted for publication 13 September 1990.
We describe a young man who developed extensive hypothalamic dysfunction including diabetes insipidus, adipsia, hyperprolactinaemia, and poikiliothermia together with central sleep apnoea following exposure to toluene.