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Q J Med 1991; 78: 145-153
© 1991 Association of Physicians

research-article

Mycobacterial Infections After Renal Transplantation

RM HIGGINS, AP CAHN, D PORTER, AJ RICHARDSON, RG MITCHELL, JM HOPKIN* and PJ MORRIS

From the Nuffield Department of Surgery Transplant Unit, University of Oxford, Churchill Hospital Headington, Oxford OX3 7LJ *Osler Chest Unit, Churchill Hospital Headington, Oxford OX3 7LJ

Accepted for publication 6 March 1990.

Mycobacterial infections occurred in 11 of 633 (1.7 per cent) recipients of successful renal transplants. There were no cases of tuberculosis in patients receiving chemoprophylaxis, but amongst those who did not receive prophylaxis disease occurred in six of the 27 (22 per cent) high-risk patients. The major cause of morbidity during treatment was renal allograft rejection, largely due to reduction in immunosuppressive drug therapy.


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