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QJM Advance Access originally published online on October 23, 2008
QJM 2009 102(1):3-16; doi:10.1093/qjmed/hcn140
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© The Author 2008. Published by Oxford University Press on behalf of the Association of Physicians. All rights reserved. For Permissions, please email: journals.permissions@oxfordjournals.org

Ethnicity and peripheral artery disease

P.C. Bennett1,2, S. Silverman2, P.S. Gill3 and G.Y.H. Lip1

From the 1University Department of Medicine, 2Department of Vascular Surgery, City Hospital, Birmingham B18 7QH and 3Department of Primary Care and General Practice University of Birmingham, Edgbaston, Birmingham B15 2TT, UK

Address correspondence to Prof. G.Y.H. Lip, University Department of Medicine, City Hospital, Birmingham B18 7QH, UK. email: g.y.h.lip{at}bham.ac.uk


  Abstract

Peripheral arterial disease (PAD) is an important healthcare problem and is an indicator of widespread atherosclerosis in other vascular territories, such as the cerebral and coronary circulations. PAD is associated with considerable morbidity and mortality. Most population-based studies investigating PAD prevalence and risk factors for its development and progression have been based on predominantly White ethnic groups. Much less is known about the characteristics of this disease in other ethnic groups. Understanding the epidemiology of PAD amongst ethnic minority groups is relevant, given that the population of minority ethnic groups in countries such as the United Kingdom rose by 53% between 1991 and 2001 and is expected to rise further in the future. This article aims to provide an overview of possible pathophysiological differences between ethnic groups for PAD, focussing predominantly on South Asians (people originating from India, Bangladesh and Pakistan) and Blacks (people of Black Caribbean and Black African descent) as these groups comprise the majority of all ethnic minorities in the United Kingdom.


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E. Zintzaras and N. Zdoukopoulos
A Field Synopsis and Meta-Analysis of Genetic Association Studies in Peripheral Arterial Disease: The CUMAGAS-PAD Database
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[Abstract] [Full Text] [PDF]


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