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QJM Advance Access originally published online on March 19, 2008
QJM 2008 101(6):487-491; doi:10.1093/qjmed/hcn034
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© The Author 2008. Published by Oxford University Press on behalf of the Association of Physicians. All rights reserved. For Permissions, please email: journals.permissions@oxfordjournals.org

Diagnosing metabolic syndrome in type 2 diabetes: does it matter?

S.H. Song1 and C.A. Hardisty2

From the 1Diabetes Centre, Northern General Hospital and 2Diabetes Centre, Royal Hallamshire Hospital, Sheffield, UK

Address correspondence to Dr Soon H Song, Diabetes Centre, Northern General Hospital, Herries Road, Sheffield S5 7AU, UK. email: soon_song{at}hotmail.com

Received 28 October 2007 and in revised form 18 February 2008


  Abstract

Background: Metabolic syndrome (MetS) is used as a clinical tool to identify individuals at risk of cardiovascular disease (CVD) but its clinical value in the management of type 2 diabetes mellitus (T2DM) remains uncertain.

Aim: To determine the prevalence and clinical usefulness of MetS among patients with T2DM attending diabetes clinics in a large teaching hospital.

Design: Prospective observational study.

Methods: Prevalence of MetS was determined by using International Diabetes Federation (IDF) and National Cholesterol Education Program Adult Treatment Panel III (NCEP-ATPIII) definitions in relation to age, sex, diabetes duration and history of CVD.

Results: A total of 390 patients were included in this study. Both IDF and NCEP-ATPIII definitions identified high prevalence of MetS in male and female patients (IDF: male vs. female, 91.7 vs. 94.8% and NCEP-ATPIII: male vs. female, 87.6 vs. 94.2%) regardless of age (below vs. above 40 yrs, ~70–75 vs. ~90–95% with both definitions), diabetes duration (below vs. above 5 yrs, ~85–90 vs. 90–95% with both definitions) and history of CVD (without vs. with CVD, ~90 vs. ~95% with both definitions). Central obesity was common reflected by mean waist circumference of ~113 cm regardless of age and gender. Among those who did not have IDF-defined MetS, ~60% had at least two CVD risk factors. Both definitions similarly classified ~94% of the patients as either having or not having MetS.

Discussion: Both definitions can be used interchangeably to diagnose MetS. However, the clinical usefulness of MetS is debatable given the very high prevalence of this condition in T2DM.


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Home page
 British Journal of Diabetes & Vascular DiseaseHome page
S. H Song and T. A Gray
Management of type 2 diabetes and lipids: a critique of the NICE guidelines 2008
The British Journal of Diabetes & Vascular Disease, March 1, 2009; 9(2): 69 - 74.
[Abstract] [PDF]


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