QJM Advance Access originally published online on February 2, 2008
QJM 2008 101(3):237-239; doi:10.1093/qjmed/hcn004
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From nurture to Nature—the story of the Aberdeen asthma dietary hypothesis
From the Department of Environmental and Occupational Medicine, University of Aberdeen and Institute of Occupational Medicine, Edinburgh, Scotland, UK
Address correspondence to Professor Anthony Seaton, 8 Avon Grove Cramond, Edinburgh EH4 6RF, Scotland, UK. email: a.seaton{at}abdn.ac.uk
Received 22 November 2007 and in revised form 19 December 2007
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This article recounts the story of the dietary hypothesis for the rise in asthma and allergies from the first idea to publication of papers showing an association of maternal diet during pregnancy with rise of asthma in the offspring at 2 and 5 years. The nutrient most consistently associated with this endpoint is vitamin E, and it is suggested that reductions in the intake of this vitamin during pregnancy over past decades could explain up to a third of the excess cases of childhood asthma.
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